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Drug Name | SJB3-019A |
Trade Name | |
Synonyms | |
Drug Descriptions |
SJB3-019A irreversibly inhibits USP1, resulting in decreased USP1 deubiquitinylating activity and downstream DNA repair pathway signaling, and reduced tumor cell viability (PMID: 28270494). |
DrugClasses | USP1 inhibitor 7 |
CAS Registry Number | 2070015-29-9 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bortezomib + SJB3-019A | Bortezomib SJB3-019A | 0 | 0 |
Lenalidomide + SJB3-019A | Lenalidomide SJB3-019A | 0 | 0 |
Pomalidomide + SJB3-019A | Pomalidomide SJB3-019A | 0 | 0 |
Ricolinostat + SJB3-019A | Ricolinostat SJB3-019A | 0 | 0 |
SJB3-019A | SJB3-019A | 0 | 0 |