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Drug Name | PF-06747143 |
Trade Name | |
Synonyms | PF 06747143|PF06747143 |
Drug Descriptions |
PF-06747143 is a CXCR4 antagonist, which inhibits CXCR4 and CXCL12-mediated cell signaling, potentially resulting in cell death and inhibition of tumor cell metastasis (PMID: 28526063, PMID: 29296751). |
DrugClasses | CXCR4 Inhibitor 15 |
CAS Registry Number | NA |
NCIT ID | C131572 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Azacitidine + Decitabine + PF-06747143 | Azacitidine Decitabine PF-06747143 | 0 | 1 |
Bendamustine + PF-06747143 | Bendamustine PF-06747143 | 0 | 0 |
Cytarabine + Daunorubicin + PF-06747143 | Cytarabine Daunorubicin PF-06747143 | 0 | 1 |
PF-06747143 | PF-06747143 | 0 | 1 |