Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Bendamustine |
Trade Name | Treanda |
Synonyms | Ribomustin|SyB L-0501|SDX-105 |
Drug Descriptions |
Treanda (bendamustine) is an alkylating agent with unique mechanisms, resulting in increased DNA damage and base-excision DNA repair pathway induction, and potentially leading to decreased growth of tumors, including those resistant to other alkylating agents (PMID: 18172283, PMID: 19117340, PMID: 19224851). Treanda (bendamustine) is FDA approved for use in chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma (FDA.gov). |
DrugClasses | Chemotherapy - Alkylating 18 |
CAS Registry Number | 16506-27-7 |
NCIT ID | C73261 |