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Drug Name | H3B-6545 |
Trade Name | |
Synonyms | SERCA H3B6545|H3B 6545 |
Drug Descriptions |
H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that targets both wild-type and mutant ESR1, which may result in antitumor activity (PMID: 35642432). |
DrugClasses | Hormone - Anti-estrogens 29 |
CAS Registry Number | 2052130-80-8 |
NCIT ID | C142980 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
H3B-6545 | H3B-6545 | 0 | 1 |
H3B-6545 + Palbociclib | H3B-6545 Palbociclib | 0 | 1 |