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Drug Name | CB-103 |
Trade Name | |
Synonyms | CB103|CB 103 |
Drug Descriptions |
CB-103 is a small molecule inhibitor of NOTCH signaling via inhibition of the NOTCH transcriptional activation complex, which may result in antitumor efficacy (Cancer Res 2016;76(14 Suppl):Abstract nr 338, PMID: 32601208). |
DrugClasses | NOTCH Inhibitor (Pan) 5 |
CAS Registry Number | HY-135145 |
NCIT ID | C175580 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + CB-103 | Abemaciclib CB-103 | 0 | 1 |
Anastrozole + CB-103 | Anastrozole CB-103 | 0 | 1 |
CB-103 | CB-103 | 0 | 1 |
CB-103 + Lenvatinib | CB-103 Lenvatinib | 0 | 1 |
CB-103 + Letrozole | CB-103 Letrozole | 0 | 1 |
CB-103 + Venetoclax | CB-103 Venetoclax | 0 | 1 |