NOX66
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| Drug Name | NOX66 |
| Trade Name | |
| Synonyms | NOX 66|NOX-66 |
| Drug Descriptions |
NOX66 is a suppository formulation of idronoxil, which inhibits PI3K/Akt signaling via blockade of ENOX2, thereby potentially increasing the sensitivity of cancer cells to chemotherapeutics (PMID: 34306271). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C132257 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + NOX66 | Carboplatin NOX66 | 0 | 0 |
| Doxorubicin + NOX66 | Doxorubicin NOX66 | 0 | 1 |
| lutetium Lu 177 vipivotide tetraxetan + NOX66 | NOX66 lutetium Lu 177 vipivotide tetraxetan | 0 | 0 |
| NOX66 | NOX66 | 0 | 2 |
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