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Drug Name | NOX66 |
Trade Name | |
Synonyms | NOX 66|NOX-66 |
Drug Descriptions |
NOX66 is a suppository formulation of idronoxil, which inhibits PI3K/Akt signaling via blockade of ENOX2, thereby potentially increasing the sensitivity of cancer cells to chemotherapeutics (PMID: 34306271). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C132257 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + NOX66 | Carboplatin NOX66 | 0 | 0 |
Doxorubicin + NOX66 | Doxorubicin NOX66 | 0 | 1 |
lutetium Lu 177 vipivotide tetraxetan + NOX66 | NOX66 lutetium Lu 177 vipivotide tetraxetan | 0 | 0 |
NOX66 | NOX66 | 0 | 2 |