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Drug Name | lutetium Lu 177 vipivotide tetraxetan |
Trade Name | Pluvicto |
Synonyms | Lu177-PSMA-617|Vipivotide tetraxetan Lu-177 |
Drug Descriptions |
Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is a radioconjugate comprising a prostate-specific membrane antigen (PSMA) inhibitor radiolabeled with Lu177, which targets PSMA expressing cells, potentially resulting in decreased tumor growth (PMID: 25883127, PMID: 26795286, PMID: 32760622). Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is FDA approved for use in patients with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) who have received androgen receptor (AR) pathway inhibition and taxane-based chemotherapy (FDA.gov). |
DrugClasses | |
CAS Registry Number | 1703749-62-5 |
NCIT ID | C148145 |