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Drug Name | PLX2853 |
Trade Name | |
Synonyms | PLX-2853|PLX 2853 |
Drug Descriptions |
PLX2853 is a BET bromodomain inhibitor with specificity for BRD4, which may result in cell cycle arrest thereby inhibiting cell proliferation (PMID: 32717030). |
DrugClasses | BRD4 Inhibitor 10 |
CAS Registry Number | NA |
NCIT ID | C146825 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abiraterone + PLX2853 + Prednisone | Abiraterone PLX2853 Prednisone | 0 | 1 |
Carboplatin + PLX2853 | Carboplatin PLX2853 | 0 | 1 |
Olaparib + PLX2853 | Olaparib PLX2853 | 0 | 1 |
PLX2853 | PLX2853 | 0 | 3 |