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Drug Name | mRNA-2416 |
Trade Name | |
Synonyms | mRNA 2416 |
Drug Descriptions |
mRNA-2416 is a lipid nanoparticle-encapsulated mRNA encoding the ligand, TNFSF4 (OX40L, CD252), which upon translation binds to TNFRSF4 (OX40, CD134) expressed on T-lymphocytes, potentially leading to proliferation of T-cells and enhanced anti-tumor response (Cancer Res 2020;80(16 Suppl):Abstract nr CT032, NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C142137 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
mRNA-2416 | mRNA-2416 | 0 | 1 |