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Drug Name | Lexatumumab |
Trade Name | |
Synonyms | ETR2-ST01|HGS-1018|HGS-ETR2|HGS1018|TRAIL-R2 |
Drug Descriptions |
Lexatumumab (ETR2-ST01) is a monoclonal antibody that binds to and activates TRAIL receptor 2, resulting in apoptosis in TRAIL R2-expressing tumor cells (PMID: 17243490, PMID: 23071222). |
DrugClasses | |
CAS Registry Number | 845816-02-6 |
NCIT ID | C64621 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Lexatumumab | Lexatumumab | 0 | 0 |
Lexatumumab + PF-573228 | Lexatumumab PF-573228 | 0 | 0 |