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Drug Name | PF-573228 |
Trade Name | |
Synonyms | PF-573,228|PF573228|PF 573228 |
Drug Descriptions |
PF-573228 is a small molecule inhibitor of PTK2 (FAK), which may reduce cell migration and decrease focal adhesion cellular turnover, thus suppressing metastasis (PMID: 17395594, PMID: 30352800, PMID: 32349327). |
DrugClasses | FAK inhibitor 15 |
CAS Registry Number | 869288-64-2 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bosutinib + Osimertinib + PF-573228 | Bosutinib Osimertinib PF-573228 | 0 | 0 |
Gefitinib + PF-573228 | Gefitinib PF-573228 | 0 | 0 |
Lexatumumab + PF-573228 | Lexatumumab PF-573228 | 0 | 0 |
Osimertinib + PF-573228 + Saracatinib | Osimertinib PF-573228 Saracatinib | 0 | 0 |
PF-573228 | PF-573228 | 0 | 0 |