PF-573228
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| Drug Name | PF-573228 |
| Trade Name | |
| Synonyms | PF-573,228|PF573228|PF 573228 |
| Drug Descriptions |
PF-573228 is a small molecule inhibitor of PTK2 (FAK), which may reduce cell migration and decrease focal adhesion cellular turnover, thus suppressing metastasis (PMID: 17395594, PMID: 30352800, PMID: 32349327). |
| DrugClasses | FAK inhibitor 16 |
| CAS Registry Number | 869288-64-2 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bosutinib + Osimertinib + PF-573228 | Bosutinib Osimertinib PF-573228 | 0 | 0 |
| Gefitinib + PF-573228 | Gefitinib PF-573228 | 0 | 0 |
| Lexatumumab + PF-573228 | Lexatumumab PF-573228 | 0 | 0 |
| Osimertinib + PF-573228 + Saracatinib | Osimertinib PF-573228 Saracatinib | 0 | 0 |
| PF-573228 | PF-573228 | 0 | 0 |
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