Pegzilarginase
Drug Detail
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| Drug Name | Pegzilarginase |
| Trade Name | |
| Synonyms | AEB1102|AEB-1102|Co-ArgI-PEG |
| Drug Descriptions |
Pegzilarginase (AEB1102) is a modified form of human arginase (ARG1) that metabolizes arginine and decreased levels of arginine may induce autophagy and promote apoptosis (AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 869, PMID: 31954097). |
| DrugClasses | |
| CAS Registry Number | 1659310-95-8 |
| NCIT ID | C125143 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pegzilarginase | Pegzilarginase | 0 | 1 |
| Pegzilarginase + Pembrolizumab | Pegzilarginase Pembrolizumab | 0 | 1 |
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