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Drug Name | Pegzilarginase |
Trade Name | |
Synonyms | AEB1102|AEB-1102|Co-ArgI-PEG |
Drug Descriptions |
Pegzilarginase (AEB1102) is a modified form of human arginase (ARG1) that metabolizes arginine and decreased levels of arginine may induce autophagy and promote apoptosis (AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 869, PMID: 31954097). |
DrugClasses | |
CAS Registry Number | 1659310-95-8 |
NCIT ID | C125143 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Pegzilarginase | Pegzilarginase | 0 | 1 |
Pegzilarginase + Pembrolizumab | Pegzilarginase Pembrolizumab | 0 | 1 |