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Drug Name BMS-986253
Trade Name
Synonyms HuMax-IL8|MDX 018|MDX-018|BMS986253|BMS- 86253
Drug Descriptions

BMS-986253 (HuMax-IL8) is a monoclonal antibody that targets interleukin-8 (CXCL8, IL8) to prevent activation of the receptors, CXCR1 and CXCR2, in effort to prevent immune escape and tumor progression (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3091-3091).

DrugClasses
CAS Registry Number 2231258-73-2
NCIT ID C124227

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BMS-986253 BMS-986253 0 2
BMS-986253 + Cabiralizumab BMS-986253 Cabiralizumab 0 0
BMS-986253 + Decitabine and Cedazuridine BMS-986253 Decitabine and Cedazuridine 0 1
BMS-986253 + Degarelix + Nivolumab BMS-986253 Degarelix Nivolumab 0 1
BMS-986253 + Nivolumab BMS-986253 Nivolumab 0 6


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