Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | SGN-CD123A |
Trade Name | |
Synonyms | SGNCD123A|SGN CD123A |
Drug Descriptions |
SGN-CD123A is an antibody-drug conjugate comprising a CD123-targeted antibody linked to pyrrolobenzodiazepine dimers, which delivers the DNA cross-linking agent agent to CD123-expressing tumor cells, potentially resulting in increased tumor cell death and decreased tumor growth (PMID: 29142066). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C129457 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Quizartinib + SGN-CD123A | Quizartinib SGN-CD123A | 0 | 0 |
SGN-CD123A | SGN-CD123A | 0 | 1 |