SGN-CD123A
Drug Detail
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| Drug Name | SGN-CD123A |
| Trade Name | |
| Synonyms | SGNCD123A|SGN CD123A |
| Drug Descriptions |
SGN-CD123A is an antibody-drug conjugate comprising a CD123 (IL3RA)-targeted antibody linked to pyrrolobenzodiazepine dimers, which delivers the DNA cross-linking agent to CD123 (IL3RA)-expressing tumor cells, potentially resulting in increased tumor cell death and decreased tumor growth (PMID: 29142066). |
| DrugClasses | CD123 (IL3RA) Antibody 14 |
| CAS Registry Number | NA |
| NCIT ID | C129457 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Quizartinib + SGN-CD123A | Quizartinib SGN-CD123A | 0 | 0 |
| SGN-CD123A | SGN-CD123A | 0 | 1 |
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