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Drug Name | zandelisib |
Trade Name | |
Synonyms | ME401|PWT-143|PWT143|ME-401 |
Drug Descriptions |
Zandelisib (ME-401) is a selective Pi3kd inhibitor that inhibits PI3K/AKT pathway signaling to decrease cell proliferation and induce cell death (PMID: 31506873). |
DrugClasses | PIK3CD inhibitor 27 |
CAS Registry Number | 1595129-71-7 |
NCIT ID | C123925 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + Vincristine Sulfate + zandelisib | Cyclophosphamide Doxorubicin Prednisone Rituximab Vincristine Sulfate zandelisib | 0 | 1 |
Rituximab + zandelisib | Rituximab zandelisib | 0 | 2 |
Tazemetostat + zandelisib | Tazemetostat zandelisib | 0 | 1 |
zandelisib | zandelisib | 0 | 2 |