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Drug Name | Samuraciclib |
Trade Name | |
Synonyms | CT 7001|CT7001|CT-7001|ICEC0942 |
Drug Descriptions |
Samuraciclib (ICEC0942) is an orally available and selective CDK7 inhibitor that prevents Cdk7 phosphorylation to induce cell cycle arrest and apoptosis (PMID: 29545334, PMID: 32150405). |
DrugClasses | CDK7 Inhibitor 16 |
CAS Registry Number | 1805789-54-1 |
NCIT ID | C155652 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Elacestrant + Samuraciclib | Elacestrant Samuraciclib | 0 | 1 |
Fulvestrant + Samuraciclib | Fulvestrant Samuraciclib | 0 | 2 |
Giredestrant + Samuraciclib | Giredestrant Samuraciclib | 0 | 0 |
Pexidartinib + Samuraciclib | Pexidartinib Samuraciclib | 0 | 0 |
Samuraciclib | Samuraciclib | 0 | 1 |
Samuraciclib + Tamoxifen | Samuraciclib Tamoxifen | 0 | 0 |
Samuraciclib + Vepdegestrant | Samuraciclib Vepdegestrant | 0 | 1 |