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Drug Name | ASTX029 |
Trade Name | |
Synonyms | ASTX-029|ASTX 029 |
Drug Descriptions |
ASTX029 is an ERK1/2 inhibitor that prevents MAPK/ERK pathway activation, which may result in growth inhibition and tumor regression (PMID: 34330842). |
DrugClasses | ERK Inhibitor (pan) 21 ERK1 Inhibitor 2 ERK2 Inhibitor 2 |
CAS Registry Number | 2095719-92-7 |
NCIT ID | C155785 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ASTX029 | ASTX029 | 12 | 2 |
ASTX029 + Decitabine and Cedazuridine | ASTX029 Decitabine and Cedazuridine | 0 | 2 |
ASTX029 + Vemurafenib | ASTX029 Vemurafenib | 1 | 0 |