Belvarafenib
Drug Detail
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| Drug Name | Belvarafenib |
| Trade Name | |
| Synonyms | HM95573|GDC-5573|RO7223619 |
| Drug Descriptions |
Belvarafenib (HM95573) selectively inhibits RAF dimer formation, leading to inhibition of ARAF, BRAF, and CRAF activity, and potentially resulting in tumor growth inhibition (PMID: 33953400). |
| DrugClasses | RAF Inhibitor (Pan) 29 |
| CAS Registry Number | 1446113-23-0 |
| NCIT ID | C121646 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Belvarafenib + Cobimetinib | Atezolizumab Belvarafenib Cobimetinib | 0 | 0 |
| Belvarafenib | Belvarafenib | 19 | 1 |
| Belvarafenib + Cobimetinib | Belvarafenib Cobimetinib | 5 | 1 |
| Belvarafenib + Cobimetinib + Nivolumab | Belvarafenib Cobimetinib Nivolumab | 0 | 1 |
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