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Drug Name | Serplulimab |
Trade Name | |
Synonyms | HLX10|HLX-10|HLX 10 |
Drug Descriptions |
Serplulimab (HLX10) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 29932513). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | 2231029-82-4 |
NCIT ID | C156738 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + Etoposide + Serplulimab | Carboplatin Etoposide Serplulimab | 0 | 2 |
Carboplatin + Nab-paclitaxel + Serplulimab | Carboplatin Nab-paclitaxel Serplulimab | 0 | 1 |
Cisplatin + Etoposide + Serplulimab | Cisplatin Etoposide Serplulimab | 0 | 1 |
HLX60 + Serplulimab | HLX60 Serplulimab | 0 | 1 |
Serplulimab | Serplulimab | 0 | 0 |