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Drug Name ACTR087
Trade Name
Synonyms ACTR-087|ACTR 087
Drug Descriptions

ACTR087 is a chimeric construct consisting of the extracellular domain of CD16 linked to CD3zeta signaling and 41BB co-stimulatory domains delivered into human T-cells via gamma-retrovirus, which may lead to enhanced anti-tumor activity in combination with tumor-targeting antibodies (Blood 2016, 128(22):3512).

DrugClasses
CAS Registry Number NA
NCIT ID C129715

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ACTR087 ACTR087 0 0
ACTR087 + Rituximab ACTR087 Rituximab 0 1
ACTR087 + SEA-BCMA ACTR087 SEA-BCMA 0 1
ACTR087 + Trastuzumab ACTR087 Trastuzumab 0 1


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