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Drug Name | MRG-106 |
Trade Name | |
Synonyms | Cobomarsen |
Drug Descriptions |
MRG-106 (cobomarsen) is an LNA-modified oligonucleotide that inhibits the microRNA miR-155-5p, which results in increased expression of miR-155-5p silenced genes and potentially leads to decreased proliferation and increased apoptosis of tumor cells (Blood 126.23 (2015): 3802, PMID: 30125933). |
DrugClasses | |
CAS Registry Number | 1848257-52-2 |
NCIT ID | C124225 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MRG-106 | MRG-106 | 0 | 3 |