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Therapy Name | MRG-106 |
Synonyms | |
Therapy Description |
MRG-106 (cobomarsen) is an LNA-modified oligonucleotide that inhibits the microRNA miR-155-5p, which results in increased expression of miR-155-5p silenced genes and potentially leads to decreased proliferation and increased apoptosis of tumor cells (Blood 126.23 (2015): 3802, PMID: 30125933). |