IMGN632
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| Drug Name | IMGN632 |
| Trade Name | |
| Synonyms | IMGN 632|IMGN-632 |
| Drug Descriptions |
IMGN632 is an antibody-drug conjugate (ADC) comprising an anti-CD123 (IL3RA) antibody linked to a DNA alkylating indolinobenzodiazepine pseudodimer, which may induce cytotoxicity in cells expressing CD123 (IL3RA) (PMID: 29661755, PMID: 30361418). |
| DrugClasses | CD123 (IL3RA) Antibody 14 |
| CAS Registry Number | NA |
| NCIT ID | C143251 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Azacitidine + IMGN632 | Azacitidine IMGN632 | 0 | 1 |
| Azacitidine + IMGN632 + Venetoclax | Azacitidine IMGN632 Venetoclax | 0 | 1 |
| IMGN632 | IMGN632 | 0 | 2 |
| IMGN632 + Venetoclax | IMGN632 Venetoclax | 0 | 1 |
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