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Drug Name | IMGN632 |
Trade Name | |
Synonyms | IMGN 632|IMGN-632 |
Drug Descriptions |
IMGN632 is an antibody-drug conjugate comprised of an anti-CD123 antibody linked to a DNA alkylating agent, an indolinobenzodiazepine pseudodimer, which may result in cytotoxicty of cells expressing CD123 (PMID: 29661755, PMID: 30361418). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C143251 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Azacitidine + IMGN632 | Azacitidine IMGN632 | 0 | 1 |
Azacitidine + IMGN632 + Venetoclax | Azacitidine IMGN632 Venetoclax | 0 | 1 |
IMGN632 | IMGN632 | 0 | 2 |
IMGN632 + Venetoclax | IMGN632 Venetoclax | 0 | 1 |