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Drug Name IMGN632
Trade Name
Synonyms IMGN 632|IMGN-632
Drug Descriptions

IMGN632 is an antibody-drug conjugate comprised of an anti-CD123 antibody linked to a DNA alkylating agent, an indolinobenzodiazepine pseudodimer, which may result in cytotoxicty of cells expressing CD123 (PMID: 29661755, PMID: 30361418).

DrugClasses
CAS Registry Number NA
NCIT ID C143251

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + IMGN632 Azacitidine IMGN632 0 1
Azacitidine + IMGN632 + Venetoclax Azacitidine IMGN632 Venetoclax 0 1
IMGN632 IMGN632 0 2
IMGN632 + Venetoclax IMGN632 Venetoclax 0 1


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