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Drug Name | Vebreltinib |
Trade Name | |
Synonyms | Bozitinib|PLB1001|PLB-1001|APL-101|APL 101|APL101 |
Drug Descriptions |
Vebreltinib (PLB-1001) is an ATP-competitive, small molecule inhibitor of MET, which is able to permeate the blood brain barrier and may inhibit downstream signaling and block tumor growth (PMID: 30343896). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 1440964-89-5 |
NCIT ID | C129717 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Osimertinib + Vebreltinib | Osimertinib Vebreltinib | 0 | 1 |
Vebreltinib | Vebreltinib | 0 | 1 |