Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | CYC065 |
Trade Name | |
Synonyms | Fadraciclib|CYC-065|CYC 065 |
Drug Descriptions |
CYC065 (Fadraciclib) inhibits CDK2, CDK5, and CDK9, potentially resulting in decreased tumor cell growth (PMID: 28376145, PMID: 27351214, PMID: 32645016). |
DrugClasses | CDK2 Inhibitor 31 CDK5 Inhibitor 8 CDK9 Inhibitor 21 |
CAS Registry Number | 1070790-89-4 |
NCIT ID | C123902 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ABT-737 + CYC065 | ABT-737 CYC065 | 0 | 0 |
BMS986158 + CYC065 | BMS986158 CYC065 | 0 | 1 |
CYC065 | CYC065 | 2 | 3 |
CYC065 + Navitoclax | CYC065 Navitoclax | 0 | 0 |
CYC065 + Venetoclax | CYC065 Venetoclax | 0 | 1 |