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Drug Name | GSK3145095 |
Trade Name | |
Synonyms | GSK 3145095|GSK-3145095 |
Drug Descriptions |
GSK3145095 is a small molecule that inhibits RIPK1, resulting in decreased downstream signaling, and potentially leading to reduced recruitment of immunosuppressive cells in the tumor microenvironment and increased tumor cell death (PMID: 31223438). |
DrugClasses | |
CAS Registry Number | 1622849-43-7 |
NCIT ID | C156737 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GSK3145095 | GSK3145095 | 0 | 1 |
GSK3145095 + Pembrolizumab | GSK3145095 Pembrolizumab | 0 | 1 |