Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | Tesetaxel |
| Trade Name | |
| Synonyms | DJ-927 |
| Drug Descriptions |
Tesetaxel (DJ-927) is a taxane that stabilizes tubulin and inhibits microtubule disassembly, potentially resulting in increased cytotoxicity in tumor cells and decreased tumor growth (PMID: 12824894, PMID: 21547572). |
| DrugClasses | Antimicrotubule Agent 14 |
| CAS Registry Number | 333754-36-2 |
| NCIT ID | C37451 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Tesetaxel | Atezolizumab Tesetaxel | 0 | 1 |
| Capecitabine + Tesetaxel | Capecitabine Tesetaxel | 0 | 2 |
| Itraconazole + Tesetaxel | Itraconazole Tesetaxel | 0 | 0 |
| Nivolumab + Tesetaxel | Nivolumab Tesetaxel | 0 | 1 |
| Pembrolizumab + Tesetaxel | Pembrolizumab Tesetaxel | 0 | 1 |
| Rifampin + Tesetaxel | Rifampin Tesetaxel | 0 | 0 |
| Tesetaxel | Tesetaxel | 0 | 1 |