hEGFRvIII-CD3 bi-scFv
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| Drug Name | hEGFRvIII-CD3 bi-scFv |
| Trade Name | |
| Synonyms | BRiTE|hEGFRvIII-CD3-bi-scFv Bispecific T-cell Engager |
| Drug Descriptions |
hEGFRvIII-CD3 bi-scFv is a bispecific antibody that targets both EGFRvIII and CD3, resulting in the activation of T-lymphocytes, increased tumor cell lysis, and reduced tumor growth (PMID: 29703821, PMID: 32273346, PMID: 32735564). |
| DrugClasses | CD3 Antibody 119 EGFR Antibody 73 |
| CAS Registry Number | NA |
| NCIT ID | C180836 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| hEGFRvIII-CD3 bi-scFv | hEGFRvIII-CD3 bi-scFv | 0 | 1 |
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