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Drug Name hEGFRvIII-CD3 bi-scFv
Trade Name
Synonyms BRiTE|hEGFRvIII-CD3-bi-scFv Bispecific T-cell Engager
Drug Descriptions

hEGFRvIII-CD3 bi-scFv is a bispecific antibody that targets both EGFRvIII and CD3, resulting in the activation of T-lymphocytes, increased tumor cell lysis, and reduced tumor growth (PMID: 29703821, PMID: 32273346, PMID: 32735564).

DrugClasses CD3 Antibody 99 EGFR Antibody 60
CAS Registry Number NA
NCIT ID C180836

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Therapy Name Drugs Efficacy Evidence Clinical Trials
hEGFRvIII-CD3 bi-scFv hEGFRvIII-CD3 bi-scFv 0 1


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