Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | hEGFRvIII-CD3 bi-scFv |
Trade Name | |
Synonyms | BRiTE|hEGFRvIII-CD3-bi-scFv Bispecific T-cell Engager |
Drug Descriptions |
hEGFRvIII-CD3 bi-scFv is a bispecific antibody that targets both EGFRvIII and CD3, resulting in the activation of T-lymphocytes, increased tumor cell lysis, and reduced tumor growth (PMID: 29703821, PMID: 32273346, PMID: 32735564). |
DrugClasses | CD3 Antibody 99 EGFR Antibody 60 |
CAS Registry Number | NA |
NCIT ID | C180836 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
hEGFRvIII-CD3 bi-scFv | hEGFRvIII-CD3 bi-scFv | 0 | 1 |