ATI-450
Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | ATI-450 |
| Trade Name | |
| Synonyms | CDD-450|MK2Pi|Zunsemetinib |
| Drug Descriptions |
ATI-450 is a small molecule that selectively inhibits MK2 (MAPKAPK2) activation by p38alpha (MAPK14), potentially leading to reduced metastatic tumor growth (PMID: 30093561, PMID: 29549113). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C182621 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ATI-450 | ATI-450 | 0 | 0 |
| ATI-450 + Capecitabine | ATI-450 Capecitabine | 0 | 1 |
| ATI-450 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin | ATI-450 Fluorouracil Irinotecan Leucovorin Oxaliplatin | 0 | 1 |
| ATI-450 + Paclitaxel | ATI-450 Paclitaxel | 0 | 0 |
CKB BOOST