Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | ATI-450 |
Trade Name | |
Synonyms | CDD-450|MK2Pi|Zunsemetinib |
Drug Descriptions |
ATI-450 is a small molecule that selectively inhibits MK2 (MAPKAPK2) activation by p38alpha (MAPK14), potentially leading to reduced metastatic tumor growth (PMID: 30093561, PMID: 29549113). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C182621 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ATI-450 | ATI-450 | 0 | 0 |
ATI-450 + Capecitabine | ATI-450 Capecitabine | 0 | 1 |
ATI-450 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin | ATI-450 Fluorouracil Irinotecan Leucovorin Oxaliplatin | 0 | 1 |
ATI-450 + Paclitaxel | ATI-450 Paclitaxel | 0 | 0 |