AZD7648
Drug Detail
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| Drug Name | AZD7648 |
| Trade Name | |
| Synonyms | AZD-7648|AZD 7648 |
| Drug Descriptions |
AZD7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK), which potentially enhances genomic instability and sensitizes tumor cells to DNA-damaging agents (PMID: 31699977, PMID: 31851518). |
| DrugClasses | DNA_PK Inhibitor 9 |
| CAS Registry Number | 2230820-11-6 |
| NCIT ID | C168692 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD7648 | AZD7648 | 3 | 1 |
| AZD7648 + Olaparib | AZD7648 Olaparib | 3 | 1 |
| AZD7648 + Pegylated liposomal doxorubicin | AZD7648 Pegylated liposomal doxorubicin | 0 | 1 |
| AZD7648 + Radiotherapy | AZD7648 Radiotherapy | 0 | 0 |
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