Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | AsiDNA |
Trade Name | |
Synonyms | |
Drug Descriptions |
AsiDNA is an oligodeoxyribonucleotide drug that acts as a DNA repair pathway antagonist by mimicking double-stranded DNA breaks and subsequently recruiting DNA repair proteins, thereby preventing the repair of other DNA damaged sites, and thus, potentially leading to increased cell death and inhibition of cell proliferation (PMID: 27559053, PMID: 32839491). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AsiDNA | AsiDNA | 0 | 2 |
AsiDNA + AZD2461 | AZD2461 AsiDNA | 0 | 0 |
AsiDNA + Carboplatin | AsiDNA Carboplatin | 0 | 1 |
AsiDNA + Carboplatin + Paclitaxel | AsiDNA Carboplatin Paclitaxel | 0 | 1 |
AsiDNA + Iniparib | AsiDNA Iniparib | 0 | 0 |
AsiDNA + Niraparib | AsiDNA Niraparib | 0 | 1 |
AsiDNA + Olaparib | AsiDNA Olaparib | 0 | 1 |
AsiDNA + Rucaparib | AsiDNA Rucaparib | 0 | 0 |
AsiDNA + Talazoparib | AsiDNA Talazoparib | 0 | 0 |
AsiDNA + Veliparib | AsiDNA Veliparib | 0 | 0 |