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Drug Name Veliparib
Trade Name
Synonyms ABT-888
Drug Descriptions

Veliparib (ABT-888) is a PARP1 and PARP2 inhibitor, which inhibits DNA repair and induces lethality in homologous recombination deficient cells, and may enhance the sensitivity of chemotherapeutic agents (PMID: 26251615, PMID: 31074636, PMID: 32452601).

DrugClasses PARP Inhibitor (Pan) 31
CAS Registry Number 912444-00-9
NCIT ID C60768

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Prednisone + Veliparib Abiraterone Prednisone Veliparib 0 1
Aldoxorubicin + Cyclophosphamide + Veliparib Aldoxorubicin Cyclophosphamide Veliparib 0 1
AsiDNA + Veliparib AsiDNA Veliparib 0 0
Atezolizumab + Veliparib Atezolizumab Veliparib 0 0
AZD6482 + Veliparib AZD6482 Veliparib 1 0
B02 + Veliparib B02 Veliparib 0 0
Bendamustine + Rituximab + Veliparib Bendamustine Rituximab Veliparib 0 0
Bendamustine + Veliparib Bendamustine Veliparib 0 0
Berzosertib + Cisplatin + Veliparib Berzosertib Cisplatin Veliparib 0 1
Bevacizumab + Veliparib Bevacizumab Veliparib 0 1
Capecitabine + Temozolomide + Veliparib Capecitabine Temozolomide Veliparib 0 1
Capecitabine + Veliparib Capecitabine Veliparib 0 1
Carboplatin + Dinaciclib + Veliparib Carboplatin Dinaciclib Veliparib 0 0
Carboplatin + Etoposide + Veliparib Carboplatin Etoposide Veliparib 0 4
Carboplatin + Nivolumab + Paclitaxel + Pemetrexed Disodium + Veliparib Carboplatin Nivolumab Paclitaxel Pemetrexed Disodium Veliparib 0 1
Carboplatin + Paclitaxel + Pemetrexed Disodium + Veliparib Carboplatin Paclitaxel Pemetrexed Disodium Veliparib 0 1
Carboplatin + Paclitaxel + Veliparib Carboplatin Paclitaxel Veliparib 0 1
Carboplatin + Topotecan + Veliparib Carboplatin Topotecan Veliparib 0 1
Carboplatin + Veliparib Carboplatin Veliparib 0 0
Cisplatin + Gemcitabine + Veliparib Cisplatin Gemcitabine Veliparib 0 0
Cisplatin + Veliparib Cisplatin Veliparib 0 1
Cisplatin + Veliparib + Vinorelbine Cisplatin Veliparib Vinorelbine 0 0
Cyclophosphamide + Veliparib Cyclophosphamide Veliparib 0 0
CYT01B + Veliparib CYT01B Veliparib 0 0
Dinaciclib + Veliparib Dinaciclib Veliparib 0 1
Floxuridine + Veliparib Floxuridine Veliparib 0 1
Fluorouracil + Irinotecan + Leucovorin + Veliparib Fluorouracil Irinotecan Leucovorin Veliparib 0 1
Fluorouracil + Oxaliplatin + Veliparib Fluorouracil Oxaliplatin Veliparib 2 0
Foretinib + Veliparib Foretinib Veliparib 0 0
Irinotecan + Veliparib Irinotecan Veliparib 1 0
Lapatinib + Veliparib Lapatinib Veliparib 0 1
Liposomal irinotecan + Veliparib Liposomal irinotecan Veliparib 0 1
M4076 + Veliparib M4076 Veliparib 0 0
Mitomycin C + Veliparib Mitomycin C Veliparib 0 1
Nivolumab + Veliparib Nivolumab Veliparib 0 1
Pegylated liposomal doxorubicin + Veliparib Pegylated liposomal doxorubicin Veliparib 0 1
Radiotherapy + Temozolomide + Veliparib Radiotherapy Temozolomide Veliparib 0 0
Radiotherapy + Veliparib Radiotherapy Veliparib 2 0
SN-38 + Veliparib SN-38 Veliparib 0 0
Temozolomide + Veliparib Temozolomide Veliparib 3 3
Topotecan + Veliparib Topotecan Veliparib 0 2
Veliparib Veliparib 5 29


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