Minnelide
Drug Detail
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| Drug Name | Minnelide |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
Minnelide is a water-soluble prodrug of the naturally derived diterpene triepoxide, triptolide, which induces apoptosis and inhibits cell proliferation, leading to reduced tumor growth (PMID: 28192510, PMID: 32733649). |
| DrugClasses | |
| CAS Registry Number | 1254702-87-8 |
| NCIT ID | C111762 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Irinotecan + Minnelide | Irinotecan Minnelide | 0 | 0 |
| Minnelide | Minnelide | 0 | 2 |
| Minnelide + Osimertinib | Minnelide Osimertinib | 0 | 1 |
| Minnelide + Plicamycin | Minnelide Plicamycin | 0 | 0 |
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