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Drug Name | MEDI2228 |
Trade Name | |
Synonyms | MEDI-2228|anti-BCMA ADC MEDI2228|Anti-BCMA/PBD MEDI2228 |
Drug Descriptions |
MEDI2228 is an antibody-drug conjugate comprising a BCMA targeted antibody linked to a pyrrolobenzodiazepine dimer, which delivers the DNA cross-linking agent to BCMA-expressing tumor cells, potentially resulting in decreased tumor growth (Blood (2017) 130 (Supplement 1): 3153, PMID: 32060401). |
DrugClasses | TNFRSF17 Antibody 20 |
CAS Registry Number | NA |
NCIT ID | C150127 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MEDI2228 | MEDI2228 | 0 | 1 |