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Drug Name | CAR.k.28 cells |
Trade Name | |
Synonyms | ATLCAR.k.28|ATLCAR.kappa.28 |
Drug Descriptions |
CAR.k.28 cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor targeting the Kappa-light chain antibody linked to CD28 endodomain, which potentially induces cytotoxicity against Kappa-positive tumor cells (PMID: 16926291). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bendamustine + CAR.k.28 cells + Fludarabine | Bendamustine CAR.k.28 cells Fludarabine | 0 | 1 |
CAR.k.28 cells | CAR.k.28 cells | 0 | 1 |
CAR.k.28 cells + Cyclophosphamide + Fludarabine | CAR.k.28 cells Cyclophosphamide Fludarabine | 0 | 1 |