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Drug Name CAR.k.28 cells
Trade Name
Synonyms ATLCAR.k.28|ATLCAR.kappa.28
Drug Descriptions

CAR.k.28 cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the kappa-light chain antibody linked to CD28 endodomain, which potentially induce cytotoxicity against Kappa-positive tumor cells (PMID: 16926291, NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C175446

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + CAR.k.28 cells + Fludarabine Bendamustine CAR.k.28 cells Fludarabine 0 1
CAR.k.28 cells CAR.k.28 cells 0 1
CAR.k.28 cells + Cyclophosphamide + Fludarabine CAR.k.28 cells Cyclophosphamide Fludarabine 0 1


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