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Drug Name | IPH5201 |
Trade Name | |
Synonyms | IPH-5201|IPH 5201|IPH52 |
Drug Descriptions |
IPH5201 is a monoclonal antibody that binds to and inhibits soluble and membrane-bound CD39, resulting in decreased ATP hydrolysis, which potentially leads to activation of T-lymphocytes and anti-tumor immune response (PMID: 31116985, PMID: 31244820). |
DrugClasses | Adenosine Targeting 23 CD39 Antibody 5 |
CAS Registry Number | NA |
NCIT ID | C175591 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + Durvalumab + IPH5201 + Paclitaxel | Carboplatin Durvalumab IPH5201 Paclitaxel | 0 | 1 |
Carboplatin + Durvalumab + IPH5201 + Pemetrexed Disodium | Carboplatin Durvalumab IPH5201 Pemetrexed Disodium | 0 | 1 |
Cisplatin + Durvalumab + IPH5201 + Pemetrexed Disodium | Cisplatin Durvalumab IPH5201 Pemetrexed Disodium | 0 | 1 |
Durvalumab + IPH5201 | Durvalumab IPH5201 | 0 | 1 |
Durvalumab + IPH5201 + Oleclumab | Durvalumab IPH5201 Oleclumab | 0 | 1 |
IPH5201 | IPH5201 | 0 | 1 |