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Drug Name | BI-2852 |
Trade Name | |
Synonyms | BI 2852|BI2852 |
Drug Descriptions |
BI-2852 is a KRAS inhibitor that binds to the pocket between the switch I and II regions and inhibits interaction with GEF, GAP, and effector proteins, potentially blocking activation of downstream signaling and inhibiting cell proliferation (PMID: 31332011). |
DrugClasses | KRAS Inhibitor 18 |
CAS Registry Number | 2375482-51-0 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BI-2852 | BI-2852 | 0 | 0 |
BI-2852 + Binimetinib + Radiotherapy | BI-2852 Binimetinib Radiotherapy | 0 | 0 |