Brexucabtagene autoleucel
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| Drug Name | Brexucabtagene autoleucel |
| Trade Name | Tecartus |
| Synonyms | KTE-X19|KTEX19|KTE X19 |
| Drug Descriptions |
Tecartus (brexucabtagene autoleucel) are autologous T-cells engineered to express an anti-CD-19 chimeric antigen receptor (CAR), which may potentially target CD-19-expressing tumor cells (PMID: 32242358). Tecartus (brexucabtagene autoleucel) is FDA approved for use in adult patients with relapsed or refractory mantle cell lymphoma and patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (FDA.gov). |
| DrugClasses | CD19 Immune Cell Therapy 72 |
| CAS Registry Number | NA |
| NCIT ID | C170439 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Brexucabtagene autoleucel | Brexucabtagene autoleucel | 0 | 5 |
| Brexucabtagene autoleucel + Cyclophosphamide + Fludarabine | Brexucabtagene autoleucel Cyclophosphamide Fludarabine | 0 | 4 |
| Brexucabtagene autoleucel + Pirtobrutinib | Brexucabtagene autoleucel Pirtobrutinib | 0 | 1 |
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