Debio 0123
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| Drug Name | Debio 0123 |
| Trade Name | |
| Synonyms | Debio-0123|Debio0123 |
| Drug Descriptions |
Debio 0123 is an ATP-competitive inhibitor of Wee1 that suppresses CDK1 phosphorylation, which may lead to tumor growth inhibition (Cancer Res 2019;79(13 Suppl):Abstract nr 4423). |
| DrugClasses | WEE1 Inhibitor 8 |
| CAS Registry Number | NA |
| NCIT ID | C173426 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Debio 0123 | Carboplatin Debio 0123 | 0 | 1 |
| Carboplatin + Debio 0123 + Etoposide | Carboplatin Debio 0123 Etoposide | 0 | 1 |
| Debio 0123 | Debio 0123 | 0 | 1 |
| Debio 0123 + RP-6306 | Debio 0123 RP-6306 | 0 | 1 |
| Debio 0123 + Sacituzumab govitecan-hziy | Debio 0123 Sacituzumab govitecan-hziy | 0 | 1 |
| Debio 0123 + Temozolomide | Debio 0123 Temozolomide | 0 | 1 |
CKB BOOST