Zedoresertib
Drug Detail
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| Drug Name | Zedoresertib |
| Trade Name | |
| Synonyms | Debio-0123|Debio0123|Debio 0123 |
| Drug Descriptions |
Zedoresertib (debio 0123) is an ATP-competitive inhibitor of Wee1 that suppresses CDK1 phosphorylation, which may lead to tumor growth inhibition (Cancer Res 2019;79(13 Suppl):Abstract nr 4423). |
| DrugClasses | WEE1 Inhibitor 8 |
| CAS Registry Number | 2243882-74-6 |
| NCIT ID | C173426 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Etoposide + Zedoresertib | Carboplatin Etoposide Zedoresertib | 0 | 1 |
| Carboplatin + Zedoresertib | Carboplatin Zedoresertib | 0 | 1 |
| RP-6306 + Zedoresertib | RP-6306 Zedoresertib | 0 | 1 |
| Sacituzumab govitecan-hziy + Zedoresertib | Sacituzumab govitecan-hziy Zedoresertib | 0 | 1 |
| Temozolomide + Zedoresertib | Temozolomide Zedoresertib | 0 | 1 |
| Zedoresertib | Zedoresertib | 0 | 1 |
CKB BOOST