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| Drug Name | TBio-6517 |
| Trade Name | |
| Synonyms | RIVAL-01 |
| Drug Descriptions |
TBio-6517 is an engineered vaccinia virus that expresses the Flt3 ligand, an antibody targeting CTLA4, and the cytokine IL-12, which may lead to immune activation and increased anti-tumor immune response, and decreased tumor cell proliferation (NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C174049 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Pembrolizumab + TBio-6517 | Pembrolizumab TBio-6517 | 0 | 1 |
| TBio-6517 | TBio-6517 | 0 | 1 |