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Drug Name | OT-82 |
Trade Name | |
Synonyms | OT82|OT 82 |
Drug Descriptions |
OT-82 inhibits nicotinamide phosphoribosyltransferase (NAMPT), which results in a decrease in the level of NAD, potentially leading to decreased tumor growth (PMID: 31896781). |
DrugClasses | NAMPT Inhibitor 7 |
CAS Registry Number | NA |
NCIT ID | C162742 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Irinotecan + OT-82 | Irinotecan OT-82 | 0 | 0 |
Niraparib + OT-82 | Niraparib OT-82 | 0 | 0 |
OT-82 | OT-82 | 0 | 1 |