Safimaltib
Drug Detail
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| Drug Name | Safimaltib |
| Trade Name | |
| Synonyms | JNJ67856633|JNJ 67856633|JNJ-67856633 |
| Drug Descriptions |
Safimaltib is an inhibitor that blocks the activity of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), resulting in decreased NF-kappaB and JAK/STAT signaling, potentially leading to increased apoptosis and decreased growth of MALT1-expressing tumor cells (PMID: 39894894, NCI Drug Dictionary). |
| DrugClasses | MALT1 Inhibitor 6 |
| CAS Registry Number | 2230273-76-2 |
| NCIT ID | C160147 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Ibrutinib + Safimaltib | Ibrutinib Safimaltib | 0 | 1 |
| JNJ-64264681 + Safimaltib | JNJ-64264681 Safimaltib | 0 | 1 |
| Safimaltib | Safimaltib | 0 | 1 |
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