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Drug Name | CCR5 shRNA/TRIM5a/TAR decoy-transduced CD34+ HPCs |
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Drug Descriptions |
CCR5 shRNA/TRIM5a/TAR decoy-transduced CD34+ HPCs are patient hematopoietic progenitor cells that have been transduced using a lentiviral vector containing HIV genes for a short hairpin RNA that interferes with CCR5 expression, TRIM5a, and a TAT activation response (TAR) decoy as well as a mutated version of human CD25, which may result in resistance to HIV infection and HIV-related tumors (NCI Drug Dictionary). |
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CAS Registry Number | NA |
NCIT ID | C123931 |