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Drug Name | Ad5-survivin-transduced autologous DC vaccine |
Trade Name | |
Synonyms | Autologous DC:AdmS |
Drug Descriptions |
Ad5-survivin-transduced autologous DC vaccine consists of autologous dendritic cells engineered to carry a replication defective adenovirus type 5 vector (Ad5) that encodes a survivin antigen, which potentially activates a cytotoxic T-lymphocyte response against survivin-expressing tumor cells, resulting in cell death (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C128860 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ad5-survivin-transduced autologous DC vaccine | Ad5-survivin-transduced autologous DC vaccine | 0 | 0 |
Ad5-survivin-transduced autologous DC vaccine + Filgrastim + PCV13 vaccine | Ad5-survivin-transduced autologous DC vaccine Filgrastim PCV13 vaccine | 0 | 1 |