Anti-hCD70 CAR-T cells
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| Drug Name | Anti-hCD70 CAR-T cells |
| Trade Name | |
| Synonyms | Anti-hCD70 CAR T cells|Anti-hCD70 CAR autologous PBLs |
| Drug Descriptions |
Anti-hCD70 CAR-T cells are patient-derived peripheral blood lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD70 and containing the extracellular region of CD27 fused to TNFRSF9 (4-1BB) and CD3-zeta, which potentially inhibit the growth of CD70-expressing tumors (PMID: 27803044). |
| DrugClasses | CD70 Immune Cell Therapy 11 |
| CAS Registry Number | NA |
| NCIT ID | C129593 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldesleukin + Anti-hCD70 CAR-T cells | Aldesleukin Anti-hCD70 CAR-T cells | 0 | 1 |
| Anti-hCD70 CAR-T cells | Anti-hCD70 CAR-T cells | 0 | 0 |
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