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Therapy Name | Anti-hCD70 CAR-T cells |
Synonyms | |
Therapy Description |
Anti-hCD70 CAR-T cells are patient-derived peripheral blood lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD70 and containing the extracellular region of CD27 fused to TNFRSF9 (4-1BB) and CD3-zeta, which potentially inhibit the growth of CD70-expressing tumors (PMID: 27803044). |