Anti-CD33 CAR-T cells
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| Drug Name | Anti-CD33 CAR-T cells |
| Trade Name | |
| Synonyms | CD33CART|CART-33 TCR zeta:CD137 Cells|Anti-CD33 CART cells |
| Drug Descriptions |
Anti-CD33 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD33 linked to TNFRSF9 (4-1BB) and CD3zeta signaling domains, which potentially induce lysis of CD33-expressing tumor cells and inhibit tumor growth (PMID: 25721896). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C107190 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Anti-CD33 CAR-T cells | Anti-CD33 CAR-T cells | 0 | 4 |
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