VAX014
Drug Detail
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| Drug Name | VAX014 |
| Trade Name | |
| Synonyms | VAX-IP|VAX 014|VAX-014 |
| Drug Descriptions |
VAX014 is bacterial minicell therapeutic comprising E. coli engineered to express Invasin and the bacterial toxin perfringolysin O (PFO), which delivers the toxin to tumor cells expressing Integrin alpha3beta1 or alpha5beta1, potentially resulting in increased tumor cell apoptosis and decreased tumor growth (PMID: 27919942, PMID: 27119118). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C170742 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| VAX014 | VAX014 | 0 | 2 |
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