RET inact mut
Gene Variant Detail

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Gene RET
Variant inact mut
Impact List unknown
Protein Effect loss of function
Gene Variant Descriptions RET inact mut indicates that this variant results in a loss of function of the Ret protein. However, the specific amino acid change has not been identified.
Associated Drug Resistance
Category Variants Paths

RET mutant RET inact mut

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RET inact mut pheochromocytoma not applicable N/A Guideline Risk Factor Germline pathogenic RET mutations result in multiple endocrine neoplasia type 2 (MEN2), which is associated with increased risk of developing pheochromocytoma (NCCN.org). detail...